Leasing medical office space in Soho is an important decision that requires planning and research. The size of the office, amount of rooms, cost per square-foot and proximity to major neighborhood attractions and traffic are all details that our agents will help you with. We will make sure you are comfortable and confident about your real estate purchase. Our listings are carefully chosen with your business type in mind so you can find a quality space faster with all the things you need.


55 Listings
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Soho | 521 Broadway, New York, NY 10012

Built for immediate productivity, this furnished office features 1 private office, 1 large conference room, 1 meeting room, open seating for 42 workstations, and a premium pantry. Skylights, exposed ceilings, and hardwood flooring create an authentic SoHo loft environment. The existing installation is available through August 2027.

3,379 sqft
Lease Term Aug 2027
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Most NYC landlord restrict us from listing the asking rental price.

Many landlords are offering significant concessions, construction allowances, and free rent.

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Hudson Square | 1 SoHo Sq, New York, NY 10013

Configured for approximately one hundred ninety-three workstation seats supported by seven conference rooms and eleven additional meeting rooms. Layout emphasizes collaboration with a high volume of enclosed meeting spaces and no dedicated private offices. Open benching core is balanced by perimeter and interior rooms to create a highly functional, team-oriented environment.

27,344 sqft
Lease Term Thru Feb 2031
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Most NYC landlord restrict us from listing the asking rental price.

Many landlords are offering significant concessions, construction allowances, and free rent.

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Soho | 462 Broadway, New York, NY 10013

Six workstations are supported within a clean open layout, complemented by one private office and immediate access to shared conference facilities in the building. The space blends exposed loft character with a fully furnished, move-in ready setup, including a stocked pantry for day-to-day convenience. Ideal for a small, focused team, this suite delivers efficiency, flexibility, and a polished Soho presence.

1,200 sqft
Lease Term Negotiable
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Most NYC landlord restrict us from listing the asking rental price.

Many landlords are offering significant concessions, construction allowances, and free rent.

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Hudson Square | 1 SoHo Sq, New York, NY 10013

Designed for a large, collaborative team, the layout supports approximately one hundred seventy workstation seats distributed across multiple open benching zones. Five enclosed conference rooms are complemented by nine additional meeting and huddle rooms, providing ample space for presentations, team collaboration, and private discussions. The balance of high-density seating and abundant enclosed meeting areas creates an efficient, scalable environment suited for organizations with active, meeting-driven workflows.

27,344 sqft
Lease Term Thru Feb 2031
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Most NYC landlord restrict us from listing the asking rental price.

Many landlords are offering significant concessions, construction allowances, and free rent.

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Soho | 72 Spring St, New York, NY 10012

The unit includes multiple large benching areas that comfortably accommodate 100+ workstations, supported by a full perimeter of glass-fronted team rooms and private offices. Four well-proportioned conference rooms are distributed across the layout, including two large boardroom-style spaces and two medium-sized breakout or huddle rooms. The floor also features multiple lounge and collaboration areas, dual-entry reception access, and excellent natural light on three sides.

22,990 sqft
Lease Term Negotiable
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Most NYC landlord restrict us from listing the asking rental price.

Many landlords are offering significant concessions, construction allowances, and free rent.

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Soho | 46 Greene St, New York, NY 10013

This full-floor office offers a dynamic and efficient layout featuring 49 workstation seats, 3 private offices, and 2 glass-enclosed conference rooms designed for seamless collaboration. A spacious open-plan work area is complemented by dedicated breakout zones, a sophisticated yet functional work environment suited for a range of business needs.

7,300 sqft
Lease Term March 2026
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Most NYC landlord restrict us from listing the asking rental price.

Many landlords are offering significant concessions, construction allowances, and free rent.

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Soho | 46 Greene St, New York, NY 10013

Designed to accommodate a seamless workflow, this full-floor office features 49 workstation seats, 3 private offices, and 2 glass-enclosed conference rooms that blend privacy with an open, collaborative feel. A thoughtfully arranged open work area maximizes efficiency, move-in-ready opportunity for businesses seeking a refined yet dynamic workspace.

7,300 sqft
Lease Term March 2026
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Most NYC landlord restrict us from listing the asking rental price.

Many landlords are offering significant concessions, construction allowances, and free rent.

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Soho | 434 Broadway, New York, NY 10013

This full-floor office space features a well-balanced layout with seven private offices, a spacious open work area, and a dedicated reception area. The space includes a fully equipped kitchen, two modern restrooms, and flexible perimeter rooms that can serve as executive offices, conference rooms, or breakout spaces. Large windows throughout provide excellent natural light, while high ceilings and industrial accents create an inspiring work environment designed for productivity and collaboration.

6,951 sqft
Lease Term April 2025
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Most NYC landlord restrict us from listing the asking rental price.

Many landlords are offering significant concessions, construction allowances, and free rent.

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Soho | 451 Broadway, New York, NY 10013

This full-floor office features 11 private offices, an open workspace with seating for approximately 87, a dedicated media hub, and a spacious conference room equipped for seamless presentations. A well-appointed kitchen and breakout lounge offer comfortable gathering spaces, while three bathrooms and multiple storage areas enhance convenience. The layout is designed for efficiency, blending private and collaborative work areas with abundant natural light.

13,000 sqft
Lease Term Negotiable
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Most NYC landlord restrict us from listing the asking rental price.

Many landlords are offering significant concessions, construction allowances, and free rent.

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Soho | 75 Spring St, New York, NY 10012

HIGH-END PREBUILD Full Floor Office on Soho's Best Corner Natural Light pours in from all four sides Exposed Loft Ceilings and Hardwood Floors

6,400 sqft
Lease Term Negotiable
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Most NYC landlord restrict us from listing the asking rental price.

Many landlords are offering significant concessions, construction allowances, and free rent.

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