Soho Retail Property for Lease

Located at the intersection of Soho and the Lower East Side, 55–59 Chrystie Street presents a rare opportunity to lease a full-floor commercial space offering both high visibility and adaptable functionality. The ground-floor suite spans an expansive footprint with high ceilings, full glass frontage, and direct street-level access—making it ideally suited for medical, gallery, or showroom use. Set within a distinctive corner building that bridges the creative energy of Soho with the evolving Bowery corridor, the space combines architectural character with modern infrastructure, providing a uniquely versatile environment for tenants seeking both prestige and practicality.

No private offices, conference rooms, or built-in workstations are currently configured in this layout, making it ideal for gallery, showroom, or experiential retail use. The space consists of one open-floor rectangular room with high ceilings and clean finishes, allowing flexible programming without spatial constraints. Tenants can easily introduce modular desks, display partitions, or semi-private zones based on operational needs.

Prime Restaurant Space for Rent - Perfect Opportunity for Your Culinary Vision Property Highlights: Size: 4000 sq ft (Two floors + 2000 sq ft usable basement) Condition: Requires Major Renovation but potential to customize the space to fit your unique concept

Ground Floor 2,127 SF Mezzanine 641 SF Open floor plan Potential to add non-contiguous storage space Historic columns

Charming Soho store with great visibility on vibrant block. Large, floor-to-ceiling glass display window. All uses considered. Pop-ups welcome. 400 sf LL included

Currently a smoke shop. Lease up May 2025 all uses considered. Space base venting from prior tenant

Boutique Space suitable for all uses. Currently Spoke & Weal. Across from Rapkin-Gayle Plaza Park. Great cotenants ranging from fashion, food, and fitness. In close vicinity to two great hotels.

Rare small store opportunity. No food uses. Small non contiguous storage space available. 16' of frontage

Turnkey store on sought-after Soho block. Full frontage with two display windows. Blade signage.

Soho is a vibrant downtown neighborhood home to an extensive collection of national and international retailers. Compelling demographics and strong tourism bolster the allure of Soho, while six subway lines contribute to the tremendous volume of pedestrian traffic in this dynamic community.